Saxagliptin, also known by the brand name Onglyza, is a popular drug used to help manage type 2 diabetes. It was co-developed in 2007 by Bristol-Myers Squibb and AstraZeneca. After an article published in 2016, the FDA added a warning for consumers about the increased risk of heart failure caused by taking Saxagliptin.
What is Onglyza (Saxagliptin) Used For?
Onglyza is used to help improve HbA1C levels in individuals with type 2 diabetes. It is often used in combination with the drug Metformin. The combined use of Saxagliptin and Metformin have shown to have greater efficacy than Saxagliptin alone.
Side Effects from using Onglyza and Saxagliptin
The most common side effects from using Onglyza include upper respiratory infections, urinary tract infections and headaches. In some cases Onglyza has been found to cause joint pain. In rare cases it has been shown to increase the risk of heart failure.
Is it safe to use Onglyza?
As with any prescription drug, it is very important that Onglyza use is managed by a physician. Based on your personal health, your physician may prescribe Onglyza or different medication to help manage type 2 diabetes.
Are there any current lawsuits related to Onglyza?
There have been several lawsuits filed by consumers who experienced heart failure after using Saxagliptin. These lawsuits were consolidated into a multidistrict litigation in 2018. In addition, there were several lawsuits which alleged that Onglyza caused pancreatic cancer. However these cases were dismissed in 2016 and no others have been filed. The Onglyza lawsuits concerning heart failure are still active.